Potential answers for "Impede in a major way"

⭐⭐⭐⭐ HOGTIE
⭐⭐ BOG
⭐⭐ ESTOP
⭐⭐ HUGELY
⭐⭐ DETER
⭐⭐ SHORTCIRCUIT
⭐⭐ HINDER
⭐⭐ SLOW
⭐⭐ DAM
⭐⭐ RETARD

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