1. To trouble aggressively, to harass.
  2. To annoy, irritate.
    Billy's professor was vexed by his continued failure to improve his grades.
  3. To cause (mental) suffering to; to distress.
  4. To twist, to weave.
  5. To be irritated; to fret.
  6. To toss back and forth; to agitate; to disquiet.

The above text is a snippet from Wiktionary: vex
and as such is available under the Creative Commons Attribution/Share-Alike License.

Need help with a clue?
Try your search in the crossword dictionary!