1. The most extreme or furthest point of something.
  2. An extreme measure.
  3. A hand or foot.
    Guillian-Barre syndrome causes one to not be able to move one's extremities.
  4. A limb

The above text is a snippet from Wiktionary: extremity
and as such is available under the Creative Commons Attribution/Share-Alike License.

Need help with a clue?
Try your search in the crossword dictionary!