Potential answers for "What remained in Pandora's box"

⭐⭐⭐⭐ HOPE
⭐⭐⭐ ILLS
⭐⭐⭐ CANOFWORMS
⭐⭐⭐ OPENACANOFWORMS
⭐⭐⭐ ERASMUS
⭐⭐⭐ RENE
⭐⭐⭐ EVILS

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Where Columbia is: Abbr.   Med. test    Was fast . . . or wasn't