Potential answers for "Sedative drug, informally"

⭐⭐⭐⭐ TRANQ
⭐⭐⭐ OPIATE
⭐⭐⭐ DOWNER
⭐⭐⭐ TRANK
⭐⭐ HYPNOTIC
⭐⭐ DOSED
⭐⭐ METH
⭐⭐ CALMED
⭐⭐ OPIOID

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