Potential answers for "Render less effective"

⭐⭐⭐⭐ IMPAIR
⭐⭐⭐ DEFUSE
⭐⭐⭐ IMPAIRS
⭐⭐⭐ MAR
⭐⭐⭐ WATERDOWN
⭐⭐⭐ DEHORN
⭐ STARKER

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Bad place for a breach   Beginning to exist   Idea beginning