Potential answers for "Legacy of a sort"

⭐⭐⭐⭐ GENES
⭐ PRUDE
⭐ MENSCH
⭐ TWITTERFEED
⭐ NAIF
⭐ ATHEISM
⭐ HEN
⭐ CUR
⭐ SOMEBODY
⭐ ARISTO

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Mainstay of protein engineering   Not necessarily precisely   As in