Potential answers for "It's a downer"

⭐⭐⭐⭐ QUAALUDE
⭐⭐⭐⭐ OPIATE
⭐⭐ TRANQ
⭐⭐ NIX
⭐⭐ SOT
⭐⭐ NEGATIVENANCY
⭐⭐ SHOWER
⭐⭐ AXE

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