Potential answers for "It may be taken at the start of a trip"

⭐⭐⭐⭐ LSD
⭐⭐ SETOFF
⭐⭐ EGO
⭐⭐ EMBARK
⭐⭐ TAKEOFF
⭐⭐ BUSDEPOT

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Discoverer of the principle behind F=ma   Sure thing!   "___ voyage!"