Potential answers for "It can knock you out"

⭐⭐⭐⭐ ETHER
⭐⭐⭐⭐ OPIATE
⭐⭐⭐⭐ ANESTHESIA
⭐⭐⭐ ETHERS
⭐⭐⭐ MICKEYFINN
⭐⭐ HOMER
⭐⭐ ELO
⭐⭐ FLU

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Realm from 800-1806: Abbr.   Cheer    "... all snug in __ beds"