Potential answers for "Initial shock?"

⭐⭐⭐⭐ OMG
⭐⭐ ELL
⭐⭐ JCREW
⭐ ELMER
⭐ ALVIN
⭐ REACT
⭐ OPEN
⭐ ANTE
⭐ ABSORBER
⭐ GASP

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Certain vaccine target   Word has it!   At some point