Potential answers for "Depths of despair"

⭐⭐⭐⭐ NADIR
⭐⭐⭐⭐ NADIRS
⭐⭐ CHINUP
⭐⭐ BROKENHEART
⭐⭐ NOHOPE
⭐⭐ LOWS
⭐⭐ AQUANAUT
⭐⭐ GORKI
⭐⭐ XXX

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First name at Woodstock   Red-cased import   1898 chemistry discovery