Potential answers for "Cause of irritation"

⭐⭐⭐⭐ SNIT
⭐⭐⭐⭐ PEEVE
⭐⭐ STYE
⭐⭐ BRISTLE
⭐⭐ SNEEZE
⭐⭐ ITCH
⭐⭐ RASH
⭐⭐ BUGBEAR

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