1. To hurt the feelings of; to displease; to make angry; to insult.
  2. To feel or become offended, take insult.
  3. To physically harm, pain.
  4. To annoy, cause discomfort or resent.
  5. To sin, transgress divine law or moral rules.
  6. To transgress or violate a law or moral requirement.
  7. To cause to stumble; to cause to sin or to fall.

The above text is a snippet from Wiktionary: offend
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